KMID : 0614620110580060332
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Korean Journal of Gastroenterology 2011 Volume.58 No. 6 p.332 ~ p.337
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Endoscopic Findings and Clinical Significance of Portal Hypertensive Colopathy
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Jung In-Bum
Lee Tae-Hee Lim Seong-Min Ryu Ki-Hyun Kim Yong-Seok Kim Sun-Moon Im Euyi-Hyeog Huh Kyu-Chan Choi Young-Woo Kang Young-Woo
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Abstract
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Background/Aims: The endoscopic findings and clinical relevance of portal hypertensive colopathy are not well described in Korea. We aimed to do a retrospective study of mucosal changes in the colon of patients with liver cirrhosis and to find their association with clinical characteristics.
Methods: We reviewed the clinical data and endoscopic findings of 48 patients with liver cirrhosis and 48 patients, matched for age and sex, with irritable bowel disease (IBS) who underwent colonoscopy over a 5 year span.
Results: Patients with liver cirrhosis were more likely to have colitis-like lesions and vascular abnormalities than IBS patients. Low platelet count (p=0.005) and severe esophageal varices (p=0.011) were associated with portal hypertensive colopathy, whereas the etiologies and severity of cirrhosis were not associated with these findings.
Conclusions: Portal hypertensive colopathy can be defined with colitis-like lesions or vascular lesions. These lesions are more frequently present in patients with more severe esophageal varices and thrombocytopenia.
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KEYWORD
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Liver cirrhosis, Portal hypertension, Colopathy
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